Mouse Poly Adp Ribose Polymerase 2, PARP2 ELISA Kit, 96T Bottles This gene also functions as

This gene also functions as an antisense transcript in the posttranscriptional regulation of the endothelial nitric oxide synthase 3 gene

Defects in EIF2B4 are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy

May have roles in neural function

Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site

The protein encoded by this gene is a mediator of mitochondrial fusion

Mouse Poly Adp Ribose Polymerase 2, PARP2 ELISA Kit, 96T Bottles This gene also functions asPoly ADP ribosyltransferase that mediates poly ADP ribosylation of proteins and plays a key role in DNA repair (PubMed: 10364231). Mediates glutamate, aspartate or serine ADP ribosylation of proteins: the ADP D ribosyl group of NAD(+) is transferred to the acceptor carboxyl group of target residues and further ADP ribosyl groups are transferred to the 2' position of the terminal adenosine moiety, building up a polymer with an average chain length of