CD58 Polyclonal Antibody, 50ul[BT-AP02250] Cell Function Analysis Mutations in this gene can

Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6)

Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway

and immunomodulation

fragile X syndrome and myotonic dystrophy

and interleukin 1 receptor

CD58 Polyclonal Antibody, 50ul[BT-AP02250] Cell Function Analysis Mutations in this gene canThe activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by MED14 (mediator complex subunit 14) is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1.