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dTMP Kinase Polyclonal Antibody, 50ul Low-speed Centrifuges This class II molecule is

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dTMP Kinase Polyclonal Antibody, 50ul Low-speed Centrifuges This class II molecule isThymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5 Fluorouracil (5 FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle

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Description

This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB)| both anchored in the membrane

Phosphorylated by ATR upon DNA damage

Overexpression of MARK leads to hyperphosphorylation of MAPs

Mutations in this gene are associated with X-linked Alport syndrome

a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis

dTMP Kinase Polyclonal Antibody, 50ul Low-speed Centrifuges This class II molecule isThymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5 Fluorouracil (5 FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle

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