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Current treatments for hypoxic pulmonary hypertension primarily aim to promote vasodilation, but they do not directly address ferroptosis in pulmonary vascular remodeling

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Brain Res Rev 67:209225 Cahova M, Palenickova E, Dankova H, Sticova E, Burian M, Drahota Z, Cervinkova Z, Kucera O, Gladkova C, Stopka P (2015) Metformin prevents ischemia reperfusion-induced oxidative stress in the fatty liver by attenuation of reactive oxygen species formation