ERI1 Polyclonal Antibody, 20ul Immune Cell Preparation The BRCA2 protein contains several

The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif

the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription

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Mutations in GJA1 have been associated with oculodentodigital dysplasia

ALDH3A1 is located within the Smith-Magenis syndrome region on chromosome 17

ERI1 Polyclonal Antibody, 20ul Immune Cell Preparation The BRCA2 protein contains severalERI1, also named as HEXO, 3'HEXO and THEX1, contains one exonuclease domain and one SAP domain. The SAP domain is necessary for binding to the stem loop structure of histone mRNAs and to form the ternary complex with SLBP, but not for 3' end histone mRNA exonuclease activity. It is a RNA exonuclease that binds to the 3' end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. It is