CKR-5 Polyclonal Antibody, 100ul[BT-AP14979] Dry Bath GADD45GIP1 (GADD45G interacting protein 1)

GADD45GIP1 (GADD45G interacting protein 1) encodes a nuclear-localized protein that may be induced by p53 and regulates the cell cycle by inhibiting G1 to S phase progression

CYP3A7 is part of a cluster of related genes on chromosome 7q21

An alternative splice variant has been described but its biological nature has not been determined

Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL| as well as with COPS5/JAB1| a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP

This gene is highly expressed in leukemia cells and may be a good target for therapeutic intervention

CKR-5 Polyclonal Antibody, 100ul[BT-AP14979] Dry Bath GADD45GIP1 (GADD45G interacting protein 1)This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co receptor for macrophage tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include