SPHK1 Polyclonal Antibody, 50ul Pipette Filler Following cleavage in the bait

Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase

The protein encoded by this gene is highly similar to the Saccharomyces cerevisiae SEC15 gene product| which is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast

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TMEM55A catalyzes the degradation of phosphatidylinositol 4|5-bisphosphate (PtdIns-4|5-P2) by removing the 4-phosphate (Ungewickell et al

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SPHK1 Polyclonal Antibody, 50ul Pipette Filler Following cleavage in the baitThe protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine 1 phosphate (S1P), a lipid mediator with both intra and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein coupled receptors. This protein, and its product S1P, play a key role in TNF alpha signaling and the NF kappa B activation pathway important in