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TOP1M Polyclonal Antibody, 50ul Endonucleases & Exonucleases This protein localizes to the

SKU: 56902138264

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TOP1M Polyclonal Antibody, 50ul Endonucleases & Exonucleases This protein localizes to theThis gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Description

This protein localizes to the centrosome and functions as a component of the gamma-tubulin ring complex which plays a role in microtubule organization

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but the full-length nature of some of these variants has not been defined

It plays an important role in many biological functions

These proteins are secreted

TOP1M Polyclonal Antibody, 50ul Endonucleases & Exonucleases This protein localizes to theThis gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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