MARK1/2/3/4(Phospho Thr215) Polyclonal Antibody, 20ul Gene Editing 1998 [PubMed 9768752])

1998 [PubMed 9768752])

Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin

The protein encoded by this gene is found primarily in cerebellar Purkinje cells| where it functions as a protein phosphatase inhibitor

A related pseudogene has been identified on chromosome 9

This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates| including members of the mitogen-activated kinase (MAPK) signalling pathway

MARK1/2/3/4(Phospho Thr215) Polyclonal Antibody, 20ul Gene Editing 1998 [PubMed 9768752])Catalytic activity: ATP + a protein = ADP + a phosphoprotein.,cofactor: Magnesium.,enzyme regulation: Activated by phosphorylation on Thr 215 by STK11 in complex with STE20 related adapter alpha (STRAD alpha) pseudo kinase and CAB39.,May play a role in cytoskeletal stability.,Belongs to the protein kinase superfamily. CAMK Ser Thr protein kinase family. MARK subfamily.,Contains 1 KA1 (kinase associated) domain.,Contains 1 protein kinase