eIF4E Polyclonal Antibody, 100ul Purification |tissue specificity:Highly expressed in macrophage

|tissue specificity:Highly expressed in macrophage and in monocyte-derived dendritic cells| and thymus

damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS)

which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes

The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling

The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein

eIF4E Polyclonal Antibody, 100ul Purification |tissue specificity:Highly expressed in macrophageEukaryotic translation initiation factor 4E encoded by EIF4E is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7 methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5' cap structure. Association of this protein with the 4F complex is the rate limiting step in translation initiation. EIF4E acts as a proto oncogene,