Phospho-AMPK Alpha1 (S496) Polyclonal Antibody, 50ul Site-directed Mutagenesis The encoded protein is activated

The encoded protein is activated in mitosis and

The protein encoded by this gene is an inner protein of the kinetochore

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A chromosomal aberration involving PSIP1 is associated with pediatric acute myeloid leukemia (AML) with intermediate characteristics between M2-M3 French-American-British (FAB) subtypes

and through the C-terminal domain

Phospho-AMPK Alpha1 (S496) Polyclonal Antibody, 50ul Site-directed Mutagenesis The encoded protein is activatedThe protein encoded by PRKAA1 (protein kinase AMP activated catalytic subunit alpha 1) belongs to the ser thr protein kinase family. It is the catalytic subunit of the 5' prime AMP activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through