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Chk1(Phospho Ser345) Polyclonal Antibody, 20ul Oligo Pool and is a major subunit

SKU: 57726067757

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PLN111.00 PLN140.00

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Chk1(Phospho Ser345) Polyclonal Antibody, 20ul Oligo Pool and is a major subunitThe protein encoded by this gene belongs to the Ser Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells

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Description

and is a major subunit of positive transcription elongation factor b (p-TEFb)

Individuals homozygous for a mutation in this gene are at higher risk for type 2 diabetes and have higher levels of circulating glucose and insulin levels after glucose ingestion

It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins

CYP2D6 can vary in copy number and individuals with the ultrarapid metabolizer phenotype can have 3 or more active copies of the gene

The major form of acetylcholinesterase found in brain| muscle and other tissues is the hydrophilic species| which forms disulfide-linked oligomers with collagenous| or lipid-containing structural subunits

Chk1(Phospho Ser345) Polyclonal Antibody, 20ul Oligo Pool and is a major subunitThe protein encoded by this gene belongs to the Ser Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells

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