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HLA-DOBeta Polyclonal Antibody, 50ul Variant Libraries which bind to orphan G-protein

SKU: 57890739490

4.6
USD162.00 USD200.00

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HLA-DOBeta Polyclonal Antibody, 50ul Variant Libraries which bind to orphan G-proteinHLA DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26 28

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Description

which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2

(PMID: 20173098 ) From BLAST result

and the accumulation of insoluble dipeptide repeat protein aggregates that could be pathogenic in FTD-ALS patients (PMID: 23393093)

This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner

MIM 164860) pathway

HLA-DOBeta Polyclonal Antibody, 50ul Variant Libraries which bind to orphan G-proteinHLA DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26 28

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