Crk II Monoclonal Antibody, 100ul[BT-MCA0386] Custom RNA Oligos Modulates transcription of major myofibrillar

Modulates transcription of major myofibrillar proteins

Acetylcholinesterase hydrolyzes the neurotransmitter| acetylcholine at neuromuscular junctions and brain cholinergic synapses| and thus terminates signal transmission

Alternate transcription initiation sites result in two transcript variants of this gene

Mutations in this gene have been associated with individuals affected by severe intellectual disability| early-onset epilepsy| microcephaly| congenital cataracts| growth retardation| and spasticity (PMID: 25439727)

and expression changes have also been detected in tumor cells

Crk II Monoclonal Antibody, 100ul[BT-MCA0386] Custom RNA Oligos Modulates transcription of major myofibrillarThis gene encodes a member of an adapter protein family that binds to several tyrosine phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2 phosphotyrosine interaction. The N terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C