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Alternate splicing results in multiple transcript variants

and in the 3' UTR of transferrin receptor mRNA

and behaves as a direct c-Myc target gene

which is a regulator of light-mediated signal transduction in plant cells

MEK Kinase-1 Polyclonal Antibody, 20ul[BT-AP05333] Site-directed Mutagenesis Unleash your daring side withThe protein encoded by MAP3K1 (mitogen activated protein kinase kinase kinase 1) is a serine threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF kappa B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N