Nibrin Polyclonal Antibody, 100ul[BT-AP06020] Protein Research Based on sequence comparison

Based on sequence comparison

LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells

The gene is located in a cluster of S100 genes on chromosome 1

This tyrosine phosphatase is a nuclear protein

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase

Nibrin Polyclonal Antibody, 100ul[BT-AP06020] Protein Research Based on sequence comparisonMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.