Cathepsin B Polyclonal Antibody, 100ul[BT-AP01235] Vacuum Filter and Familial dysautonomia

and Familial dysautonomia

Mutations in this gene or some other NER components result in Xeroderma pigmentosum| a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age

Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation

the predicted protein lacks most of the C-terminus and parts of the NAD+ binding motif when compared to other species' TDH proteins

tissue repair

Cathepsin B Polyclonal Antibody, 100ul[BT-AP01235] Vacuum Filter and Familial dysautonomiaCTSB encodes a member of the C1 family of peptidases. Alternative splicing of CTSB results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and