Rat Atrial Natriuretic Peptide-converting Enzyme, CORIN ELISA Kit, 96T Palm Micro Centrifuges Acts as coreceptor with CD4

Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro) (PubMed: 9726990)

An important paralog of this gene is FOXE3

Phosphorylates PLCG1

NPHS1 is primarily expressed in renal tissues

Inhibits the formation and function of inhibitory GABAergic synapses in cerebellar Purkinje cells (By similarity)

Rat Atrial Natriuretic Peptide-converting Enzyme, CORIN ELISA Kit, 96T Palm Micro Centrifuges Acts as coreceptor with CD4Serine type endopeptidase involved in atrial natriuretic Peptide (NPPA) processing (PubMed: 17660514). Converts through proteolytic cleavage the non functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation (By similarity). Proteolytic cleavage of pro NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in