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IL-2R Gamma Polyclonal Antibody, 100ul[BT-AP04492] Transporters MARK2 encodes a member of

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IL-2R Gamma Polyclonal Antibody, 100ul[BT-AP04492] Transporters MARK2 encodes a member ofCytokine receptor common subunit gamma encoded by IL2RG is an important signaling component of many interleukin receptors, including those of interleukin 2, 4, 7 and 21, and is thus referred to as the common gamma chain. Mutations in this gene cause X linked severe combined immunodeficiency (XSCID), as well as X linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.

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Description

MARK2 encodes a member of the Par-1 family of serine/threonine protein kinases

which associates with the promoter region of the glucocorticoid receptor gene (hGR gene)

and to help regulate the expression of some genes involved in circadian rhythm

and adhesion (summary by Eiseler et al

The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis

IL-2R Gamma Polyclonal Antibody, 100ul[BT-AP04492] Transporters MARK2 encodes a member ofCytokine receptor common subunit gamma encoded by IL2RG is an important signaling component of many interleukin receptors, including those of interleukin 2, 4, 7 and 21, and is thus referred to as the common gamma chain. Mutations in this gene cause X linked severe combined immunodeficiency (XSCID), as well as X linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.

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