Sin3B Polyclonal Antibody, 100ul PCR Series The BIR domain is essential

The BIR domain is essential for inhibitory activity and interacts with caspases

This family includes the fast-

This protein is also a component of Lewy bodies in Parkinson's disease patients| and it suppresses unfolded Pael receptor-induced neuronal cell death

has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs

This protein is thought to be involved in multiple pathways including roles in the nervous system

Sin3B Polyclonal Antibody, 100ul PCR Series The BIR domain is essentialSIN3B (SIN3 Transcription Regulator Family Member B) is a Protein Coding gene. Paired amphipathic helix protein Sin3b acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. Among its related