SPTA1 Rabbit Polyclonal Antibody, 50ul ROS/Nitric Oxide Detection Down-regulated in immortalized fibroblasts isolated

Down-regulated in immortalized fibroblasts isolated after a proliferative crisis accompanied with massive cell death

Alternative splicing results in multiple transcript variants encoding distinct proteins

This gene is thought to play a role in the regulation of myofibrillogenesis

subunit:Probably interacts with CLK4

many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals

SPTA1 Rabbit Polyclonal Antibody, 50ul ROS/Nitric Oxide Detection Down-regulated in immortalized fibroblasts isolatedSpectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton and functions in the determination of cell shape arrangement of transmembrane proteins and organization of organelles. It is a tetramer made up of alpha beta dimers linked in a head to head arrangement. This gene is one member of a family of alpha spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats