CD63 Polyclonal Antibody, 50ul[BT-AP01926] Adeno-associated Virus Packaging The neutrophil cytosolic factor 1

The neutrophil cytosolic factor 1 (NCF1) gene encodes the 47 kDa cytosolic subunit of neutrophil NADPH oxidase| which produces superoxide anion

The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival

RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells

exons 2 and 3 encode the two extracellular domains

CD6 may be associated with susceptibility to multiple sclerosis (PMID: 19525953

CD63 Polyclonal Antibody, 50ul[BT-AP01926] Adeno-associated Virus Packaging The neutrophil cytosolic factor 1F12 encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two chain serine protease with an heavy chain (alpha factor XIIa) and a light chain. The heavy chain contains two fibronectin type domains, two epidermal growth factor (EGF) like domains, a kringle domain and a proline rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place