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HECW1 Polyclonal Antibody, 50ul Antibodies are less active or functional

SKU: 61289660445

4.2
DKK162.00 DKK185.00

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HECW1 Polyclonal Antibody, 50ul Antibodies are less active or functionalE3 ubiquitin protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway: Protein modification; protein ubiquitination.,Contains 1 C2 domain.,Contains 1 HECT (E6AP type E3 ubiquitin protein ligase) domain.,Contains 2 WW

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Description

are less active or functional

This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development

TBL2 is deleted in Williams-Beuren syndrome

PTM:N- and O-glycosylated

This gene is found within an intron of another gene| bladder cancer associated protein| but on the opposite strand

HECW1 Polyclonal Antibody, 50ul Antibodies are less active or functionalE3 ubiquitin protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway: Protein modification; protein ubiquitination.,Contains 1 C2 domain.,Contains 1 HECT (E6AP type E3 ubiquitin protein ligase) domain.,Contains 2 WW

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