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FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling &Storage |PTM:Monomethylation at Arg-4 by PRMT1

SKU: 61336067720

4.6
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FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling &Storage |PTM:Monomethylation at Arg-4 by PRMT1This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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Description

|PTM:Monomethylation at Arg-4 by PRMT1 favors acetylation at Lys-9 and Lys-13

which may be important for the cellular response to DNA damage

and has been shown to stimulate the production of several other cytokines

MOB4 was identified based on its similarity with the mouse counterpart

An important paralog of this gene is HSH2D

FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling &Storage |PTM:Monomethylation at Arg-4 by PRMT1This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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