IκB-alpha(Phospho Tyr305) Polyclonal Antibody, 100ul Thermo Mix The cytoplasmic peripheral membrane protein

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli

including fertilization

Up-regulated during S-phase and mitosis

insects and mammalian cells

Insulin receptor is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor

IκB-alpha(Phospho Tyr305) Polyclonal Antibody, 100ul Thermo Mix The cytoplasmic peripheral membrane proteinThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell