Plakophilin 2 Polyclonal Antibody, 100ul Serological Pipets the full length nature of

the full length nature of some of these variants has not been determined

This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases

Some of these isoforms are beta subunits

Sevral transcript variants encoding different isoforms have been found for this gene

The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond

Plakophilin 2 Polyclonal Antibody, 100ul Serological Pipets the full length nature ofPKP2 encodes a member of the arm repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. PKP2 product may regulate the signaling activity of beta catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high