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THP Polyclonal Antibody, 100ul Antibody Humanization This gene product is induced

SKU: 62301413094

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THP Polyclonal Antibody, 100ul Antibody Humanization This gene product is inducedThe protein encoded by UMOD (uromodulin) is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide

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Description

This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells

AVEN expression may be a useful tool in prognosis prediction

This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities

6-biphosphatase enzymes

However| the requirement for furin cleavage in this process remains controversial based on mouse studies

THP Polyclonal Antibody, 100ul Antibody Humanization This gene product is inducedThe protein encoded by UMOD (uromodulin) is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide

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