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Phospho-ATR (S428) Polyclonal Antibody, 50ul Multi-Layer Cell Culture System The encoded protein is a

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Phospho-ATR (S428) Polyclonal Antibody, 50ul Multi-Layer Cell Culture System The encoded protein is aThe protein encoded by ATR (ATR serine threonine kinase) belongs the PI3 PI4 kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1,

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Description

The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions| including cytokinesis| cell motility and maintenance of cell shape

The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism

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base excision repair and DNA end-joining (PubMed: 14576298

They are expressed in nearly all cells

Phospho-ATR (S428) Polyclonal Antibody, 50ul Multi-Layer Cell Culture System The encoded protein is aThe protein encoded by ATR (ATR serine threonine kinase) belongs the PI3 PI4 kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1,

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