IGF-I Receptor beta(Phospho-Tyr980) Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification Mutations in this gene as

Mutations in this gene as well as in its related proteins including D-type cyclins

This protein also shuttles through the nucleus and may function as a transcriptional co-activator

FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism

some members of this family may be involved in embryogenesis

May enhance cellular proliferation

IGF-I Receptor beta(Phospho-Tyr980) Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification Mutations in this gene asThis receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have