TGFBeta3 Polyclonal Antibody, 50ul Microplate Mixer UBE1L2 is an E1 enzyme

UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al

a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules

and their phosphorylation is essential for the Catalytic activity of the N-terminal kinase domain

Mutations in this gene result in autosomal dominant hereditary thrombophilia

An important paralog of this gene is GPR161

TGFBeta3 Polyclonal Antibody, 50ul Microplate Mixer UBE1L2 is an E1 enzymeTGFB3 encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature