MARE2 Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) and a single intracytoplasmic catalytic

and a single intracytoplasmic catalytic domain

Belongs to the phospholipase D family

The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation

Loss of sequences from human chromosome 10q has been associated with the progression of human cancers

This gene encodes a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver

MARE2 Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) and a single intracytoplasmic catalyticThe protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein binding EB1 gene family. This protein is a microtubule associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants.