UBE2H Polyclonal Antibody, 20ul Serum & Sample Tubes Incomplete proteolytic processing of APP

Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease

An important paralog of this gene is RASGEF1A

COL12A1 encodes the alpha chain of type XII collagen

TOLLIP encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components

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UBE2H Polyclonal Antibody, 20ul Serum & Sample Tubes Incomplete proteolytic processing of APPThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin activating enzymes, or E1s, ubiquitin conjugating enzymes, or E2s, and ubiquitin protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin conjugating enzyme family. The encoded protein sequence is 100% identical to the mouse