Sgo1 Polyclonal Antibody, 100ul Fluorescent Staining Alternate splice variants have been

Alternate splice variants have been described but their full length sequences have not been determined

U2AF2 and SNRNP70

In adults| higher level expression is seen in the placenta| lung| kidney| and pancreas than in the heart| brain| liver and skeletal muscle

a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif

It interacts in a complex with chromatin modifying factors

Sgo1 Polyclonal Antibody, 100ul Fluorescent Staining Alternate splice variants have beenShugoshin like 1 encoded by SGOL1 is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found