PCBP2 Polyclonal Antibody, 20ul Nucleic Acid Extraction The protein encoded by SAR1B

The protein encoded by SAR1B (secretion associated Ras related GTPase 1B) is a small GTPase that acts as a homodimer

The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle

Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE)

some members of this family may be involved in embryogenesis

The encoded protein has sequence homology to diaphanous and formin proteins within the Formin Homology (FH)1 and FH2 domains

PCBP2 Polyclonal Antibody, 20ul Nucleic Acid Extraction The protein encoded by SAR1BThe protein encoded by this gene appears to be multifunctional. Along with PCBP 1 and hnRNPK, it is one of the major cellular poly(rC) binding proteins. The encoded protein contains three K homologous (KH) domains which may be involved in RNA binding. Together with PCBP 1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence specific interaction with stem loop IV of the IRES, promoting poliovirus RNA replication