Megsin Polyclonal Antibody, 100ul ssDNA Synthesis The gene encoding this protein

The gene encoding this protein is localized to 11q12

the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53

Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome

It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z

Mutations in TSC1 have been associated with tuberous sclerosis

Megsin Polyclonal Antibody, 100ul ssDNA Synthesis The gene encoding this proteinSERPINB7 (serpin family B member 7) encodes a member of a family of proteins which function as protease inhibitors. Expression of SERPINB7 is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma, Nagashima type. Alternative splicing results in multiple transcript variants.