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EDG-2 Polyclonal Antibody, 20ul Recombinant Protein Expression Alternative splicing of BAD results

SKU: 64784190958

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EDG-2 Polyclonal Antibody, 20ul Recombinant Protein Expression Alternative splicing of BAD resultsThe lysophosphatidic acid receptor 1 encoded by LPAR1 is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion.

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Description

Alternative splicing of BAD results in two transcript variants which encode the same isoform

Naturally occurring read-through transcription occurs between the upstream gene NPHP3 (nephronophthisis 3 (adolescent)) and this gene

The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al

Multiple alternatively spliced transcript variants encoding different isoforms have been noted for FGFR2

an autosomal dominant condition

EDG-2 Polyclonal Antibody, 20ul Recombinant Protein Expression Alternative splicing of BAD resultsThe lysophosphatidic acid receptor 1 encoded by LPAR1 is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion.

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