PAPP2 Polyclonal Antibody, 100ul Yeast Expression A polymorphism at this locus

A polymorphism at this locus has been reported to be associated with susceptibility to late-onset Alzheimer's disease in some populations

This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules

coiled-coil region and arginine

The protein encoded by this gene contains a SH2 domain and a SOCS box domain

and neurogenesis

PAPP2 Polyclonal Antibody, 100ul Yeast Expression A polymorphism at this locusThis gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin like growth factor binding protein 5 and is thought to be a local regulator of insulin like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants.