Lck(Phospho Ser540) Polyclonal Antibody, 20ul Serum In addition| protein levels decrease

In addition| protein levels decrease in the presence of natural killer lytic-associated molecule| suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein

Diphthamide is a post-translationally modified histidine residue present in elongation factor 2| and is the target of diphtheria toxin

Transcript variants of this gene have been described

Probably mediates E3 ubiquitin ligase activity by functioning as the essential RING domain subunit of larger E3 complexes

Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis

Lck(Phospho Ser540) Polyclonal Antibody, 20ul Serum In addition| protein levels decreaseThis gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T cells. It contains N terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein protein interactions with phosphotyrosine containing and proline rich motifs, respectively. The protein localizes to the plasma