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Elongin A3 Polyclonal Antibody, 100ul Bottle-Top Dispenser Unlike the rat homolog| the

SKU: 6614094202

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Elongin A3 Polyclonal Antibody, 100ul Bottle-Top Dispenser Unlike the rat homolog| theThe SIII (or elongin) transcription elongation factor complex stimulates the rate of transcription elongation by RNA polymerase II by suppressing the transient pausing of the polymerase at many sites along the DNA template. This complex is a heterotrimer, composed of the transcriptionally active subunit A, A2 or A3 (or elongin A, A2 or A3) and two regulatory subunits, B and C (or elongin B and C). TCEB3C encodes subunit A3. A3 and A are ubiquitously

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Description

Unlike the rat homolog| the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements

Many alternatively spliced transcript variants exist for this gene

which suggests the antiapoptotic function of this gene in cells

Cathepsin L1 encoded by CTSL1 is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism

with multiple epiphyseal dysplasia

Elongin A3 Polyclonal Antibody, 100ul Bottle-Top Dispenser Unlike the rat homolog| theThe SIII (or elongin) transcription elongation factor complex stimulates the rate of transcription elongation by RNA polymerase II by suppressing the transient pausing of the polymerase at many sites along the DNA template. This complex is a heterotrimer, composed of the transcriptionally active subunit A, A2 or A3 (or elongin A, A2 or A3) and two regulatory subunits, B and C (or elongin B and C). TCEB3C encodes subunit A3. A3 and A are ubiquitously

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