Vav1 Polyclonal Antibody, 50ul[BT-AP09488] Pathway and Network Analysis This gene product inactivates ERK1

This gene product inactivates ERK1

Mutations in EPHA2 are the cause of certain genetically-related cataract disorders

May be required for both optimal rDNA transcription and small subunit (SSU) pre-rRNA processing at sites A

It is a constituent of perineuronal nets

Mutation in this gene was also observed in individuals with metacarpal 4-5 fusion

Vav1 Polyclonal Antibody, 50ul[BT-AP09488] Pathway and Network Analysis This gene product inactivates ERK1VAV1 is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The Proto oncogene vav is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.