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Raf-1(Phospho Ser642) Polyclonal Antibody, 20ul Organelle Studies This gene encodes a protein

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Raf-1(Phospho Ser642) Polyclonal Antibody, 20ul Organelle Studies This gene encodes a proteinThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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Description

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes| platelet dense granules| and lysosomes

also known as spinocerebellar ataxia-3

The encoded protein interacts with CD3-zeta (CD247)

Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene

ATF3 is induced by a variety of signals

Raf-1(Phospho Ser642) Polyclonal Antibody, 20ul Organelle Studies This gene encodes a proteinThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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