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NEIL1 Polyclonal Antibody, 50ul Gene Synthesis The encoded protein (AT-rich interaction

SKU: 67417861367

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EUR185.00 EUR223.00

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NEIL1 Polyclonal Antibody, 50ul Gene Synthesis The encoded protein (AT-rich interactionNEIL1 is a member of the Nei endonuclease VIII like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

The encoded protein (AT-rich interaction domain 4B) is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex

The erythroid-specific protein encoded by this gene| and the ubiquitous transcription factor CP2| form the stage selector protein (SSP) complex| which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells

The protein encoded by this gene is a member of the TNF-receptor superfamily| and contains an intracellular death domain

A mutation in this gene results in AICA-ribosiduria

single-use Serological Pipets

NEIL1 Polyclonal Antibody, 50ul Gene Synthesis The encoded protein (AT-rich interactionNEIL1 is a member of the Nei endonuclease VIII like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene.

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