DUS2L Polyclonal Antibody, 50ul DNA Synthesis Belongs to the IFRD family

Belongs to the IFRD family

PTM:Phosphorylated on tyrosines by FYN (By similarity)

Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain

Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN)

This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp)

DUS2L Polyclonal Antibody, 50ul DNA Synthesis Belongs to the IFRD familyDUS2 (dihydrouridine synthase 2) encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon induced protein kinase. DUS2 has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described