EpoR Polyclonal Antibody, 20ul[BT-AP03025] Insect Expression Multiple alternatively spliced variants encoding

Multiple alternatively spliced variants encoding different isoforms have been described

Mutations in this gene are associated with erythrocytosis familial type 4

The branched-chain alpha-ketoacid dehydrogenase complex (BCKD) is an important regulator of the valine

Basal cell adhesion molecule contains five extracellular immunoglobulin domains

which is necessary for protein synthesis

EpoR Polyclonal Antibody, 20ul[BT-AP03025] Insect Expression Multiple alternatively spliced variants encodingEPOR encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: ras MAP kinase, phosphatidylinositol 3 kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce