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VPS16 Rabbit Polyclonal Antibody, 50ul Cell Proliferation The protein encoded by this

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VPS16 Rabbit Polyclonal Antibody, 50ul Cell Proliferation The protein encoded by thisVesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps16 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes lysosomes and like their yeast counterparts

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Description

The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells

flanked by N- and C-terminal globular domains

Mutations in this gene cause the syndrome of apparent mine

Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons

It is also thought to be involved in the differentiation of male germ cells

VPS16 Rabbit Polyclonal Antibody, 50ul Cell Proliferation The protein encoded by thisVesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps16 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes lysosomes and like their yeast counterparts

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