NMRL1 Rabbit Polyclonal Antibody, 20ul Immunology An important functional component of

An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4)| a protein containing two fibronectin type III domains

also known as Lon protease

Mutations in this gene are associated with Rothmund-Thomson

The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks

Sodium-independent

NMRL1 Rabbit Polyclonal Antibody, 20ul Immunology An important functional component ofThis gene encodes an NADPH sensor protein that preferentially binds to NADPH. The encoded protein also negatively regulates the activity of NF kappaB in a ubiquitylation dependent manner. It plays a key role in cellular antiviral response by negatively regulating the interferon response factor 3 mediated expression of interferon beta. Alternative splicing of this gene results in multiple transcript variants.