AFF4 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation The PWWP2B gene is conserved

The PWWP2B gene is conserved in chimpanzee

fetal and neonatal tissues

Mutations in this gene are associated with several congenital cardiovascular malformations

The product

Both long non-coding and protein-coding RNAs are transcribed from this gene

AFF4 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation The PWWP2B gene is conservedThe protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5; 11)(q31; q31q23).