Insulin R(Phospho Thr1375) Polyclonal Antibody, 100ul Supplements Transcripts at this locus may

Transcripts at this locus may also undergo A to I editing

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor

plays an important role in replication-dependent chromatin assembly

subcellular location:Cytoplasmic before and after growth factor treatment

which suggests the antiapoptotic function of this gene in cells

Insulin R(Phospho Thr1375) Polyclonal Antibody, 100ul Supplements Transcripts at this locus mayThis gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie