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TFPI Polyclonal Antibody, 100ul Pipette Micro Tips RTKN (rhotekin) encodes a scaffold

SKU: 68763176459

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TFPI Polyclonal Antibody, 100ul Pipette Micro Tips RTKN (rhotekin) encodes a scaffoldTFPI encodes a Kunitz type serine protease inhibitor that regulates the tissue factor (TF) dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa TF proteases in an autoregulatory loop.

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Description

RTKN (rhotekin) encodes a scaffold protein that interacts with GTP-bound Rho proteins

VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm

PMID: 15805470)

|miscellaneous:Engagement of killer inhibitory receptors (KIR) disrupts the interaction of PLCG1 with LAT and blocks target cell-induced activation of PLC| maybe by inducing the dephosphorylation of LAT

is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation

TFPI Polyclonal Antibody, 100ul Pipette Micro Tips RTKN (rhotekin) encodes a scaffoldTFPI encodes a Kunitz type serine protease inhibitor that regulates the tissue factor (TF) dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa TF proteases in an autoregulatory loop.

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