ARP19 Polyclonal Antibody, 20ul Protein Post-translational Modification disease:Defects in NCF1 are the

disease:Defects in NCF1 are the cause of chronic granulomatous disease autosomal recessive cytochrome-b-positive type 1 (CGD1)

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gag/pol-like fusion protein (with an additional aspartic protease motif) from RF1/RF2 by -1 translational frameshifting (-1 FS)

Alternatively spliced transcript variants encoding different isoforms of EIF4G2 have been described

which results in the activation of several signaling cascades

ARP19 Polyclonal Antibody, 20ul Protein Post-translational Modification disease:Defects in NCF1 are theThe 19 kD cAMP regulated phosphoprotein plays a role in regulating mitosis by inhibiting protein phosphatase 2A (PP2A; see MIM 176915) (summary by Gharbi Ayachi et al., 2010